Yoeri Bemelmans

Chapter 7 96 inOJA. We primarily aimed to assesswhether therewere significant differences in (1) the number of (serious) adverse events ((S)AEs) and readmission rates; (2) postoperative improvement in patient-reported outcome measures (PROMs) and (3) total hospital costs. Materials andmethods A review protocol was developed according to the Preferred Items for Reporting Systematic Reviews and Meta-Analysis (PRISMA-P) statement [14] and registered in PROSPERO (under review: no 161688), the International Prospective Register of Systematic Reviews. Search strategy A comprehensive electronic literature search was conducted to identify eligible studies on outpatient pathways following primary hip and (partial) knee arthroplasty. Five databases (Embase, PubMed, Wiley/Cochrane Library, Clarivate Analytics/Web of Science and EBSCO/CINAHL) and three trial registers (World Health Organization portal, ClinicalTrials.gov, and PROSPERO) were searched in December 2019 for published and ongoing trials. Reference lists of included studies were also searched by two independent reviewers to identify eligible studies that were missed by the search. The full search strategies are presented in the supplementary data. Eligibility of studies Both randomized controlled trials (RCTs) and (prospective or retrospective) observational studies were included in this systematic review. Only studies that compared safety and/or efficacy outcomes (e.g. (S)AEs, readmission rates, PROMs, costs) between OJA pathways and standard inpatient pathways—following hip and/ or (partial) knee arthroplasty—were included. Results needed to be published as a full report and there were no restrictions on the date of study publication. Only studies published in English were selected. Studies were excluded if they reported on patients undergoing revision surgery, bilateral arthroplasty or arthroplasty due to traumatic conditions. Strictly descriptive studies (e.g. historical and/or editorial studies) were also excluded. Selection and data collection process Two reviewers independently extracted the search results of the different databases with the RefWorks tool (ProQuest LLC ©, 2020). The aforementioned two reviewers independently screened titles and abstracts of all studies retrieved by the literature