Yoeri Bemelmans

Safety and efficacy of outpatient hip and knee arthroplasty 97 7 search. Then the full texts of all potentially eligible studies were retrieved and independently reviewed. The decision regarding study selection was based on the inclusion criteria. Discrepancies between reviewers were discussed and, if necessary, an agreement was reached by the adjudication of a third reviewer. Data extraction and outcomes Two reviewers independently extracted the data for each included study using a predefined standardized data extraction form. The data extraction form contained informationon study characteristics (e.g. author, year, country, setting, study design, type of arthroplasty and number of selected patients), patient demographics (e.g. age, gender, bodymass index (BMI), American Society of Anesthesiologists (ASA) classification and type of anesthesia) and outcomes (e.g. complication rates, readmission rates, success rates of same-day discharge (SDD), PROMs and/or costs). To account for differences in “outpatient” definitions, studies were assigned to one of the following two categories: (1) outpatient surgery (OS); outpatient defined as discharge to their own home on the day of surgery; and (2) semi-outpatient surgery (SOS); outpatient defined as discharge within 24 h after surgery with or without an overnight stay. Studies that did not specifiy the “outpatient” definition were also included in the SOS group. Complications were defined as adverse events (AEs), including wound dehiscence, wound leakage, urinary retention/infection, pneumonia, renal disorder, and blood transfusion; or serious adverse events (SAEs), including death, sepsis, coma, (prolonged) intubation, stroke, thromboembolic event (deepvein thrombosis/pulmonary embolism), infection of the prosthesis, myocardial infarction, cardiac arrest, arrhythmia, acute renal failure, perioperative fracture, failure of prothesis, hip dislocation and/or peripheral nerve injury, and return to the operating room (all re-operations). A minimal follow-up period of 30 days was required. Patient demographics were described as means with standard deviations (SD) for continuous variables (age and BMI) and frequencies with percentages for categorical variables (gender, ASA score> II, and type of anesthesia). (S)AEs, readmission rates, and successful SDD rates were described as frequencies with percentages. PROMs and costs were reported descriptively. The two reviewers had to reach a consensus on data extraction. Any discrepancies between reviewers were discussed and, if necessary, an agreement was reached by the adjudication of a third author.