Harmen Beurmanjer

Contents Chapter 1 General Introduction 7 Part 1 Understanding the GHB using population 17 Chapter 2 Unity in diversity: a systematic review on context of use and subgroups of GHB-users. 19 Chapter 3 A qualitative approach in understanding illness perception and treatment needs in patients with GHB use disorder. 35 Chapter 4 Cognitive impairments in patients with GHB use disorder predict relapse in GHB use. 49 Part 2 Pharmacological treatment interventions for patients with GHB use disorder 61 Chapter 5 Tapering with pharmaceutical GHB or benzodiazepines for detoxification in GHB-dependent patients: a matched-subjects observational study of treatment-as-usual in Belgium and the Netherlands. 63 Chapter 6 Baclofen to prevent relapse in gamma-hydroxybutyrate (GHB)-dependent patients: a multicentre, open-label, non-randomized, controlled trial. 77 Chapter 7 Summary and Discussion 89 References Nederlandse samenvatting en discussie Dankwoord (Acknowledgements) Publications and grants Curriculum Vitae Supplements 105 117 133 139 145 149