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94 Chapter 5 study will state that we would like to investigate the information provision and decision- making process in general, without explicitly mentioning that a DA is the subject of this study. This reduces potential bias from emphasizing that the DA is an addition to usual care, as the perception of any addition to usual care may evoke improved satisfaction on itself. It will also avoid a situation where patients in the control group feel that they are withheld from a potentially helpful tool. Patients are not informed about the randomization at the hospital level. For all logistics involved todistributing andprocessing the questionnaires, the PROFILES- application will be used. ‘Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship (PROFILES)’ is a registry for the study of the physical and psychosocial impact of cancer and its treatment from a dynamic, growing population-based cohort of both short and long-term cancer survivors. PROFILES was developed in 2009 by a joint research group fromTilburg University and Comprehensive Cancer Centre South (CCCS) with a grant from the Netherlands Organization for Scientific Research (NWO) 31 . PROFILES enables data collection management, from inviting patients to participate in studies to collecting patient-reported outcomes data via web-based or mailed questionnaires and provides a supporting helpdesk. Patients can send their informed consent form, which they receive with the information letter, to PROFILES. On the informed consent form patients can indicate whether they want to receive questionnaires via email or regular mail. Approximately 1 to 2 weeks after treatment decision-making (T1) patients receive either the invitation (email) to fill in an online questionnaire or a paper version at their home address. In the case of a paper version, a stamped self-addressed envelope is provided to the patient to return the questionnaire. If patients do not fill in their questionnaires within two weeks, a reminder letter or email will be send. Patients will be assured that non-participation does not result in differential follow-up care or treatment. The PROFILES-application allows for managing the follow-up questionnaires, which are sent at 6 and 12 months following T1. Outcome measures Table 1 shows an overview of all outcome measures and the moment of measurement . Primary outcomes Primary outcome is decisional conflict. The decisional conflict scale (DCS) 32,33 evaluates the level of decisional conflict on five subscales; the feeling of being well-informed; the clarity of values; the feeling of support during the decision-making process; the feeling