Rick Schreurs

17 General introduction 36 Thibault B, Ritter P, Bode K, Calo L, Mondesert B, Mangual JO, et al. Dynamic programming of atrioventricular delay improves electrical synchrony in a multicenter cardiac resynchronization therapy study. Heart Rhythm. 2019;16(7):1047-56. 37 Varma N, O’Donnell D, Bassiouny M, Ritter P, Pappone C, Mangual J, et al. Programming Cardiac Resynchronization Therapy for Electrical Synchrony: Reaching Beyond Left Bundle Branch Block and Left Ventricular Activation Delay. J Am Heart Assoc. 2018;7(3). 38 Abraham WT, Gras D, Yu CM, Guzzo L, Gupta MS, Committee FS. Rationale and design of a randomized clinical trial to assess the safety and efficacy of frequent optimization of cardiac resynchronization therapy: the Frequent Optimization Study Using the QuickOpt Method (FREEDOM) trial. Am Heart J. 2010;159(6):944-8 e1. 39 Porciani MC, Rao CM, Mochi M, Cappelli F, Bongiorno G, Perini AP, et al. A real-time three- dimensional echocardiographic validation of an intracardiac electrogram-based method for optimizing cardiac resynchronization therapy. Pacing Clin Electrophysiol. 2008;31(1):56-63. 40 Rickards AF, Bombardini T, Corbucci G, Plicchi G. An implantable intracardiac accelerometer for monitoring myocardial contractility. The Multicenter PEA Study Group. Pacing Clin Electrophysiol. 1996;19(12 Pt 1):2066-71. 41 Brugada J, Delnoy PP, Brachmann J, Reynolds D, Padeletti L, Noelker G, et al. Contractility sensor-guided optimization of cardiac resynchronization therapy: results from the RESPOND- CRT trial. Eur Heart J. 2016. 42 Ritter P, Delnoy PP, Padeletti L, Lunati M, Naegele H, Borri-Brunetto A, et al. A randomized pilot study of optimization of cardiac resynchronization therapy in sinus rhythm patients using a peak endocardial acceleration sensor vs. standard methods. Europace. 2012;14(9):1324-33. 43 Strik M, van Middendorp LB, Vernooy K. Animal models of dyssynchrony. J Cardiovasc Transl Res. 2012;5(2):135-45. 44 Marrouche NF, Pavia SV, Zhuang S, Kim YJ, Tabata T, Wallick D, et al. Nonexcitatory stimulus delivery improves left ventricular function in hearts with left bundle branch block. J Cardiovasc Electrophysiol. 2002;13(7):691-5. 45 Liu L, Tockman B, Girouard S, Pastore J, Walcott G, KenKnight B, et al. Left ventricular resynchronization therapy in a canine model of left bundle branch block. Am J Physiol Heart Circ Physiol. 2002;282(6):H2238-44. 46 Verbeek XA, Vernooy K, Peschar M, Cornelussen RN, Prinzen FW. Intra-ventricular resynchronization for optimal left ventricular function during pacing in experimental left bundle branch block. J Am Coll Cardiol. 2003;42(3):558-67. 47 Verbeek XA, Vernooy K, Peschar M, Van Der Nagel T, Van Hunnik A, Prinzen FW. Quantification of interventricular asynchrony during LBBB and ventricular pacing. Am J Physiol Heart Circ Physiol. 2002;283(4):H1370-8. 48 Vernooy K, Cornelussen RN, Verbeek XA, Vanagt WY, van Hunnik A, Kuiper M, et al. Cardiac resynchronization therapy cures dyssynchronopathy in canine left bundle-branch block hearts. Eur Heart J. 2007;28(17):2148-55. 49 Lee AWC, Costa CM, Strocchi M, Rinaldi CA, Niederer SA. Computational Modeling for Cardiac Resynchronization Therapy. J Cardiovasc Transl Res. 2018;11(2):92-108. 50 Arts T, Delhaas T, Bovendeerd P, Verbeek X, Prinzen FW. Adaptation to mechanical load determines shape and properties of heart and circulation: the CircAdapt model. Am J Physiol Heart Circ Physiol. 2005;288(4):H1943-54. 51 Lumens J, Delhaas T, Kirn B, Arts T. Three-wall segment (TriSeg) model describing mechanics and hemodynamics of ventricular interaction. Ann Biomed Eng. 2009;37(11):2234-55. 52 Huntjens PR, Ploux S, Strik M, Walmsley J, Ritter P, Haissaguerre M, et al. Electrical Substrates Driving Response to Cardiac Resynchronization Therapy: A Combined Clinical-Computational Evaluation. Circ Arrhythm Electrophysiol. 2018;11(4):e005647. 53 Jones S, Lumens J, Sohaib SMA, Finegold JA, Kanagaratnam P, Tanner M, et al. Cardiac resynchronization therapy: mechanisms of action and scope for further improvement in cardiac function. Europace. 2017;19(7):1178-86. 1