Timo Soeterik

109 External validation of the Martini Nomogram TABLE 1. Baseline characteristics of the validation cohort (N = 550) Validation cohort Mean (SD, min/max) or N (%) No. of patients 550 Age (years) 64.6 (5.6, 42 - 76) Preoperative PSA (ng/ml) 10.4 (8.6, 0.5 – 77) Clinical T-stage a T1c T2a T2b T2c T2 T3 Missing 317 (58) 107 (18) 16 (3) 17 (3) 44 (8) 43 (8) 6 (1) MRI T-stage T0 T2a T2b T2c T2 T2/T3 (EPE uncertain) T3a T3b T4 Missing 49 (9) 147 (27) 27 (5) 74 (14) 39 (7) 55 (10) 127 (23) 26 (5) 4 (1) 2 (0) Biopsy type TRUS-guided systematic MRI-guided target TRUS + MRI-guided 335 (61) 53 (10) 162 (29) Pathological T-stage T2 T2a T2b T2c T3a T3b T4 1 (0) 62 (11) 7 (1) 208 (38) 202 (37) 69 (13) 1 (0) Surgical Margin Positive Negative 187 (34) 363 (66) a Based on digital rectal examination, b In case of uncertain EPE. Percentages may not add up to 100% due to rounding. 6