Timo Soeterik

MRI T-stage for LNI Risk Prediction 155 MSKCC 2018 Threshold (%) DRE T-stage mpMRI T-stage Patients in whom ePLND is not / is recommended (%) Patients below cut- off without / with LNI (%) Patients above cut-off without / with LNI (%) ePLND spared (%) LNI missed (%) Patients in whom ePLND is not / is recommended (%) Patients below cut-off without / with LNI (%) Patients above cut-off without/with LNI (%) ePLND spared (%) LNI missed (%) 10 286 (27) / 776 (73) 247 (86) / 39 (14) 514 (66) / 262 (34) 286 (27) 39 (3.7) 179 (17) / 883 (83) 160 (89) / 19 (11) 601 (68) / 282 (32) 179 (17) 19 (1.8) 11 323 (30) / 739 (70) 276 (85) / 47 (15) 485 (66) / 254 (34) 323 (30) 47 (4.4) 209 (20) / 853 (80) 186 (89) / 23 (11) 575 (67) / 278 (33) 186 (18) 23 (2.2) 12 360 (34) / 702 (66) 311 (86) / 49 (14) 450 (64) / 252 (36) 360 (34) 49 (4.6) 241 (23) / 821 (77) 212 (88) / 29 (12) 549 (67) / 272 (33) 212 (20) 29 (2.7) 13 393 (37) / 669 (63) 338 (86) / 55 (14) 423 (63) / 246 (37) 393 (37) 55 (5.2) 264 (25) / 798 (75) 230 (87) / 34 (13) 531 (67) / 267 (33) 230 (22) 34 (3.2) 14 426 (40) / 636 (60) 366 (86) / 60 (14) 395 (62) / 241 (38) 426 (40) 60 (5.6) 294 (28) / 768 (72) 256 (87) / 38 (13) 505 (66) / 263 (34) 256 (24) 38 (3.6) 15 451 (42) / 611 (58) 381 (85) / 70 (16) 380 (62) / 231 (38) 451 (42) 70 (6.6) 323 (30) / 739 (70) 282 (87) / 41 (13) 479 (65) / 260 (35) 282 (27) 41 (3.9) SUPPLEMENTARY TABLE S3. Continued

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