Timo Soeterik

156 CHAPTER 8 SUPPLEMENTARY TABLE S4 . Systematic analysis of Briganti 2012 for nomogram-derived cut-offs Briganti 2012 Threshold (%) DRE T-stage MRI T-stage Patients in whom ePLND is not / is recommended (%) Patients below cut-off without / with LNI (%) Patients above cut-off without/with LNI (%) ePLND spared (%) LNI missed (%) Patients in whom ePLND is not / is recommended (%) Patients below cut-off without / with LNI (%) Patients above cut-off without/with LNI (%) ePLND spared (%) LNI missed (%) 1 7 (0.7) / 1055 (99.3) 5 (71) / 2 (29) 756 (72) / 299 (28) 7 (0.7) 2 (0.2) 1 (0.1) / 1061 (99.9) 1 (100) / 0 (0) 761 (72) / 301 (28) 1 (0.1) 0 (0) 2 44 (4.1) / 1018 (95.9) 40 (90.9) / 4 (9.1) 721 (71) / 297 (29) 44 (4.2) 4 (0.4) 15 (1.4) / 1047 (98.6) 14 (93.3) / 1 (6.7) 747 (71) / 300 (29) 15 (1.4) 1 (0.1) 3 84 (7.9) / 978 (92.1) 75 (89) / 9 (11) 686 (70) / 292 (30) 84 (8.0) 9 (0.8) 39 (3.7) / 1023 (96.3) 35 (89.7) / 4 (10.3) 726 (71) / 297 (29) 39 (3.7) 4 (0.4) 4 142 (13) / 920 (87) 125 (88) / 17 (12) 636 (69) / 284 (31) 142 (13) 17 (1.6) 66 (6.2) / 996 (93.8) 60 (91) / 6 (9) 701 (70) / 295 (30) 66 (6.3) 6 (0.6) 5 181 (17) / 881 (83) 162 (90) / 19 (11) 599 (68) / 282 (32) 181 (17) 19 (1.8) 87 (8.2) / 975 (91.8) 79 (91) / 8 (9) 682 (70) / 293 (30) 87 (8.2) 8 (0.8) 6 233 (22) / 829 (78) 201 (86) / 32 (14) 560 (68) / 269 (32) 233 (22) 32 (3.0) 121 (11) / 941 (89) 109 (90) / 12 (10) 652 (69) / 289 (31) 121 (12) 12 (1.1) 7 278 (26) / 784 (74) 241 (87) / 37 (13) 520 (66) / 264 (34) 278 (26) 37 (3.5) 158 (15) / 904 (85) 142 (90) / 16 (10) 619 (68) / 285 (32) 158 (15) 16 (1.5) 8 338 (32) / 724 (68) 291 (86) / 47 (14) 470 (65) / 254 (35) 338 (32) 47 (4.4) 193 (19) / 869 (81) 171 (89) / 22 (11) 590 (68) / 279 (32) 193 (18) 22 (2.1)