Timo Soeterik

66 CHAPTER 4 TABLE 1. Baseline characteristics of the overall population N (%) Patients 1683 Age (median, IQR) 68 (64 - 73) PSA (mean) 8.5 (6.0 – 13.7) Clinical T-stage T1 T2a T2b T2c T3/T4 928 (55) 488 (29) 46 (3) 62 (4) 159 (9) Highest biopsy ISUP grade 1 2 3 4 5 664 (40) 448 (27) 255 (15) 274 (16) 42 (3) Risk group (DRE) Low Intermediate High (localized) High (locally advanced) 447 (27) 658 (39) 350 (21) 228 (14) MRI T-stage T1c T2a T2b T2c T3a T3b T4 239 (14) 682 (41) 51 (3) 164 (10) 363 (17) 159 (3) 25 (2) Risk Group (mpMRI) Low Intermediate High (localized) High (locally advanced) 368 (22) 435 (26) 301 (18) 579 (34) Clinical N stage N0 N1 NX 1327 (79) 103 (6) 253 (15)