Timo Soeterik

90 CHAPTER 5 TABLE 1. Baseline characteristics of 4954 prostate lobes of 2477 patients Nerve sparing (no. of lobes [%], mean [SD]) Non-nerve sparing (no. of lobes [%], mean [SD]) No. of prostate lobes 2711 2243 Age 63.9 (6.0) 66.4 (5.4) PSA (ng/ml) 9.4 (7.3) 11.9 (12.2) PSAD (ng/ml/ml) 0.23 (0.19) 0.29 (0.27) DRE a T1 T2 T3 Unknown 2356 (87) 273 (10) 10 (0) 72 (3) 1465 (65) 572 (26) 126 (6) 80 (4) EPE on MRI a EPE absent EPE present Unknown 2182 (80) 108 (4) 421 (16) 1431 (64) 451 (20) 361 (16) ISUP biopsy grade a Benign 1 2 3 4 5 Unknown 829 (31) 1009 (37) 444 (16) 127 (5) 52 (2) 12 (0) 238 (9) 264 (12) 570 (25) 618 (28) 291 (13) 248 (11) 161 (7) 91 (4) Percentage positive cores a 0.29 (0.31) 0.54 (0.35) Surgical margin status a Negative Positive Unknown 2201 (81) 484 (18) 26 (1) 1716 (77) 505 (23) 22 (1) a Side-specific covariates on prostate lobe level. Abbreviations: PSA = prostate-specific antigen, SD = standard deviation, MHG = Martini Hospital Groningen, PSAD = prostate-specific antigen density, DRE = digital rectal examination, MRI = magnetic resonance imaging, TRUS = transrectal ultrasonography, ISUP = International Society of Urological Pathology.