M Beerens

EFFECTS OF MI PASTE PLUS ® : A 3-MONTHS FOLLOW-UP 4 65 Assessed for eligibility ( n = 184) Excluded ( n ) = 119 Not meeting inclusion criteria: At screening < 2 WSL ( n = 98) At debond < 2 WSL ( n = 6) Caries profunda ( n = 5) To old ( n = 2) Partly fixed appliance ( n = 3) Extended fluorosis dentalis ( n = 1) Systemic disease ( n = 1) Refused to participate ( n = 2) Data at screening incomplete ( n = 1) Analyzed ( n = 28) Excluded from analysis ( n = 1) No lesions detected Lost to follow-up ( n = 7) Not present at visits: ( n = 6) Decided not to participate any further ( n = 1) Allocated to intervention group A ( n = 35) Received allocated intervention ( n = 35) Lost to follow-up ( n = 3) Not present at visits: ( n = 1) Decided not to participate any further ( n = 2) Allocated to intervention group B ( n = 30) Received allocated intervention ( n = 30) Discontinued intervention due to Non-compliance ( n = 5) though include Analyzed ( n = 27) Excluded from analysis ( n = 0) Allocation Analysis Follow-up Enrolment ( n = 65) Randomization FIGURE 1. Flow of participants through the study. Group A received the CPP-ACPF product paste and Group B received the control paste.