M Beerens

90 CHAPTER 5 TABLE 2. Caries regression, determined by assessment of lesion area (A), fluorescence loss (∆F), and integrated fluorescence loss (IFL) at five different time points (in the MI Paste Plus ® group and the control group. (T1= directly after debonding, T2= 6 weeks, T3= 3 months, T4=6 months, and T5=12 months after debonding) MI Paste Plus ® , N = 25 T1 T2 T3 T4 T5 lesion size (A [mm2]) 4.65 ± 5.66  4.57 ± 6.88  4.11 ± 7.46  4.92 ± 7.17  4.63 ± 6.84  Fluorescence loss (delta F [%]) –8.07 ± 1.39  –7.57 ± 1.72  –6.99 ± 2.35  –6.67 ± 2.53* –6.25 ± 2.36* , **  Integrated fluorescence loss (delta Fx A [% x mm2]) –44.63 ± 68.11 –47.06 ± 86.43 –46.88 ± 88.46 –45.53 ± 95.43 –40.51 ± 90.83  Control, N = 26 T1 T2 T3 T4 T5 lesion size (A [mm2]) 7.34 ± 7.43  6.51 ± 7.08  6.37 ± 7.93  5.93 ± 7.13  6.02 ± 6.49  Fluorescence loss (delta F [%]) –8.94 ± 1.72  –8.44 ± 1.95  –8.09 ± 2.65  –7.93 ± 2.43  –7.10 ± 2.79*  Integrated fluorescence loss (delta Fx A [% x mm2]) –79.21 ± 105.29 –71.56 ± 90.14 –73.33 ± 93.61 –69.39 ± 86.63 –60.17 ± 74.15  Data are given as mean ± SD. *Data significant different from baseline. **Data significant different from T2.