M Beerens

EFFECTS OF MI PASTE PLUS ® : A 12-MONTHS FOLLOW-UP 5 95 TABLE 4. Enamel change, determined by International Caries Detection and Assessment System (ICDAS) at the time points of debond, blinded assessed at baseline (T1) and 12 months (T5) thereafter, in the MI Paste Plus ® group and the control group. MI Paste Plus ® n = 24 ICDAS score at T5 ICDAS score at T1 0 2 3 5 Total T1 0 229 21 250 2 87 102 3 192 3 1 2 3 Total T5 316 123 4 1 444 Control n = 24 ICDAS score at T5 ICDAS score at T1 0 2 3 5 Total T1 0 199 29 228 2 66 108 21 195 3 1 1 1 3 Total T5 266 138 22 426 Missing data n = 3. Data are given as amount counted at the two different time points. *This lesion has been restored and was scored 0 at T5. Adverse effect There was no harm experienced by the participants influencing their general health. However, in the MI Paste Plus ® group, a total of five patients had the assumption that their teeth gradually discoloured to a more yellow tone. These findings were considered incidental. No objective measures were used to test this possibly adverse effect; however, it was observed on the digital photographs of several patients in the MI Paste Plus ® group. OVERALL CONCLUSION The use of MI Paste Plus ® in orthodontic patients with subsurface enamel lesions (WSL) did not improve these lesions over the 1-year period. This was evaluated by QLF imaging, microbiological composition and acidogenicity, as well as by digital oral photographs. The lesion depth in both groups showed an overall improvement assessed by QLF (primary outcome), while the secondary optical assessment by ICDAS showed the lesions to be unchanged in both groups. No significant additional improvement was measured for patients receiving MI Paste Plus ® . The plaque composition, regarding bacterial counts, the proportions of aciduric bacteria,