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90 Chapter 5 ACKNOWLEDGEMENTS The authors are very grateful to the families of the included patients, and to the professionals who made valuable contributions to this study: JAH Bongers, J Sloof, prof. dr. CMF Dirven, dr. JS Soria van Hoeve, dr. RK Balvers, J de Groot, dr. PA Wielopolski, R Booij, dr. KH Lam, dr. V Soerdjbalie-Maikoe, dr. M de Vries, dr. AE Odink, MJP Rossius. We also thank Erasmus MC Health Care Efficiency, Stichting Coolsingel Rotterdam, and Erasmus MC Vriendenfonds for their financial support. OTHER INFORMATION Registration: Dutch Trial Register: http: /www.trialregister.nl/trialreg/admin/rctview. asp?TC=5072.