15289-s-bos

112 | Chapter 7 Compound Effect Lp(a) * Effect other lipoproteints Dicussed study on effect Lp(a) Assay used in discussed study Effect cardiovascular events Conclusion Anti-sense Apo(a) Decrease 82% Unknown Presented by Tsimikas at the American heart Association 2014. [http://ir.isispharm. com/phoenix. tml? c=222170&p=irol- newsArticle&ID=18 77550&highlight] Unknown Unknown Decreases Lp(a) The only Lp(a) specific treat- ment Lp(a), Lipoprotein (a); TG, Triglyceride; LDL-C, Low density lipoprotein-cholesterol; HDL, High density lipoprotein-cholesterol; VLDL-C, very low density lipoprotein- cholesterol; CETP, Cholesterol ester transfer protein; PCSK-9, proprotein convertase subtilisin/kexin type 9; FH, familial hypercholesterolaemia *Important note: Percentage decrease in Lp(a) from baseline cannot be compared between studies when other measurement techniques are used. Table 7.1 | Continued