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26 | Chapter 2 Inter-system variability Image acquisition time, defined as time between acquiring the first and last image, of the CHS was significantly shorter (2±1 minutes) than the PiU (4±1 minutes; p=<0.001). Results of the C-IMT measurements, and plaque scans of the healthy volunteers are depicted in table 2, and the Bland Altman plot is shown in figure 3b. For C-IMT the LOA were significantly lower on the CHS than on the PiU. However, the ICC for the C-IMT was similar. One plaque was present in the healthy controls which was seen on both devices. Figure 2.2 | Bland Altman Plots a). Bland-Altman plot of the inter-observer variability. Outer-lines: +/- 1.96*SD. b). Bland-Altman plot of the inter-system variability. Outer-lines: +/- 1.96*SD.

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