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CHAPTeR Calcific Aortic Valve disease in Familial Hypercholesterolemia: The ldl-density- Gene effect* Na l i n i M. Ra j amannan Re fer s to Sven Bos, Ger t-Jan R . ten Kate, Admi r Ded i c, L i san A. Nee f j es, Ak i ra Kurata , Janneke G. Lan- gendonk , Anho L i em, Adr i aan Moe l ker, Gabr i e l P. K res t i n , Pim J. de Feyter, Jean i ne E. Roeter s van Lennep, Koen Ni eman , Er i c J. S i jbrands *Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology. 4B a