15289-s-bos

6 91 | Lp(a) is not associated with carotid plaques and C-IMT in FH Results Data were collected from 191 FH patients. FH was genetically confirmed in 149 patients (78%), with mutations in the LDLR and APOB gene in 130 and 19 patients, respectively. PCSK-9 gene mutations were not found. The patients were 48±15 years old, and 50% were men (Table 1). Plaques in the carotid arteries were present in 64 (33.5%) patients, and the C-IMT was 0.59±0.13 mm. The coronary calcium score, measured in a subgroup of 33 asymptomatic patients was 49 (344) Agatston units, and was not associated with carotid plaques (p=0.8), and C-IMT (p=0.737). The Lp(a) levels ranged from 0.002 to 3.732 g/L with a median of 0.258 (0.620)g/L. We compared the patients with high and low Lp(a) levels (>0.3 g/L versus ≤ 0.3 g/L) Figure 6.1 | Example of a C-IMT measurement of the Panasonic CardioHealthStation. Output of the Panasonic CardioHealthStation showing one C-IMT measurement from the right common carotid artery from a lateral (135°) angle, over 1 cm. In the centre left side of the image results were displayed. The mean value displayed was combined with the other three measurements, and the mean of these four variables where used for analyses.