Lisette van Dam

Chapter 13 198 NCTI is close to implementation in practice, this is not the case for CTPP. For instance, as manual perfusion defect quantification is time-consuming and current literature does not unambiguously support the added value of perfusion imaging on top of CTPA, its applicability in daily clinical practice is still unknown. With the development and validation of artificial intelligence-based (AI) software it may be possible to more accurately and reproducible quantify perfusion defects. Automatically quantification of perfusion defects, if shown more reliably associated with prognosis, could in turn facilitate implementation of CTPP in daily practice, allowing for precision management with regard to initial treatment, duration of hospitalization and patient tailored follow-up. Studies to achieve this are currently ongoing.