Lisette van Dam

ISBN: 978-94-6416-737-5 Cover design: ©evelienjagtman.com Lay-out: Publiss | www.publiss.nl Print: Ridderprint | www.ridderprint.nl © Copyright 2021: L.F. van Dam, Leiden, The Netherlands The studies described in this thesis were performed at the Department of Thrombosis and Hemostasis of the Leiden University Medical Center, Leiden, the Netherlands. All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form by any means, electronically, mechanically, by photocopy, by recording, or otherwise, without prior written permission of the author.