Lisette van Dam

Chapter 2 20 305 patients. Baseline characteristics are described as mean with standard deviation (SD) or median with interquartile range (IQR). The primary outcome was calculated with corresponding exact 95%CI. For the secondary outcome, in which we assessed interobserver agreement of MRDTI reading, the κ -statistic was calculated. The kappa value for agreement was interpreted as follows: poor ( < 0.20), fair (0.21– 0.40), moderate (0.41–0.60), good (0.61–0.80) or excellent (0.81–1.00). 21 Analyses were performed with the use of SPSS software, version 25.0. RESULTS Patients From March 2015 to March 2019, a total of 444 consecutive patients with clinically suspected acute recurrent ipsilateral DVT of the leg were screened; 139 patients (31%) were excluded for various reasons as per predefined exclusion criteria ( Figure 2 ). The baseline characteristics of the 305 study patients are summarized in Table 1. Table 1. Baseline characteristics of 305 patients with suspected recurrent ipsilateral DVT of the leg. Mean age (+/- SD) – years 58 (16) Male – no (%) 152 (50) Median duration of complaints (IQR) – days 4 (2-7) More than 1 prior VTE episode – no (%) 98 (32) Mean time since the last DVT episode (+/- SD) – years 7 (9) Active malignancy – no (%) 18 (5.9) Immobility for > 3 days or recent long travel > 6 hours in the past 4 weeks – no (%) 21 (6.9) Trauma/surgery during the past 4 weeks – no (%) 11 (3.6) Hormone (replacement) therapy – no (%) 6 (2.0) Known genetic thrombophilia – no (%) 42 (14) SD, standard deviation.