Mark Wefers Bettink

Chapter 8 154 MitoPO2; mitochondrial oxygen tension, StO2; tissue oxygen saturation, AU; arbitrary units, MAP; mean arterial pressure, Flow; microcirculatory blood flow, Temp; skin temperature In figure 2 a single case of the neurosurgery cohort is presented. This case is notable because of long operation time. A 35-year-old woman who had surgery on a difficult- to-reach vestibular schwannoma had surgery for more than six hours. She remained hemodynamically stable throughout the operation, no vasopressors were administered during surgery. A total of 600ml blood was lost, which was supplemented with crystalloid and colloid solutions to maintain a normovolemic fluid balance. Figure 2 shows the possibility to measure stable mitoPO 2 during long period of time under stable hemodynamic conditions without losing signal quality. Figure 2 : Representative case of stable mitoPO2 measurements during an operation of more than six hours. MitoPO2; mitochondrial oxygen tension, AU; arbitrary units, Temp; skin temperature Cases Case A: pancreaticoduodenectomy with significant blood loss A 61-year-old ASA II male underwent an open pancreaticoduodenectomy according to WHIPPLE procedure because of a suspected cholangiocarcinoma. Except a previous cholecystitis for which several ERCP procedures and a laparoscopic cholecystectomy has been performed, no other details in his medical history were revealed. No medication