Mark Wefers Bettink

Monitoring of mitochondrial oxygen tension in the operating theatre 8 157 remifentanil 5 mcg/kg/h and epidural analgesia. After induction, continuous infusion of noradrenalin, starting at 0.30 mcg/kg/min and gradually increasing to 0.60 mcg/ kg/min, was necessary to maintain an adequate blood pressure. On top of standard perioperative monitoring, consisting of invasive blood pressure measurements, peripheral oxygen saturation, electrocardiography, temperature measurements and central venous pressure, COMET ® was used for mitoPO 2 measurements, and continuous total hemoglobin (SpHb) measurements were performed with a disposable Masimo Rainbow adult adhesive sensor. Figure4: Representativecaseof apatientwithcontrolledhypovolemiaandrecovery tonormovolemia. At the beginning of the surgery, 400 ml of blood was withdrawn to preserve a low central venous pressure. For the same purpose, fluid admission was kept to a minimum throughout the surgery. Only when the hepatectomy was done, fluids were given starting with an autologous blood transfusion followed by two times 500 ml of Gelofusine (figure