Mark Wefers Bettink

Chapter 1 Preface and outline	9
Chapter 2 Mind the mitochondria!	17
Chapter 3 A monitor for Cellular Oxygen METabolism (COMET): monitoring tissue oxygenation at the mitochondrial level.	43
Chapter 4 Mitochondrial oxygen monitoring with COMET: verification of calibration in man and comparison with vascular occlusion tests in healthy volunteers.	61
Chapter 5 Non-invasive versus ex vivo measurement of mitochondrial function in an endotoxemia model in rat: toward monitoring of mitochondrial therapy	83
Chapter 6 Measuring mitochondrial oxygenation and respiration in vivo in a human endotoxemia model	105
Chapter 7 Interim analysis; Feasibility study of measurement of mitochondrial function in patients with sepsis.	127
Chapter 8 Monitoring of mitochondrial oxygen tension in the operating theatre: first experiences with the novel COMET® monitor.	145
Chapter 9 Mitochondrial oxygen monitoring during surgical repair of congenital diaphragmatic hernia or esophageal atresia: a feasibility study	165
Chapter 10 Summary	183
Chapter 11 General discussion	189
Chapter 12 Nederlandse samenvatting	195
Chapter 13 Dankwoord	201
Chapter 14 Curriculum vitae	207

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