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110 | Chapter 4 column means. Results from cytotoxicity experiments are described as mean ± standard deviation of the mean (SD). A p-value of <0.05 was considered statistically significant. Acknowledgements The authors thank all voluntary blood donors, Charlotte Huijts and Roeland Lameris of VUmc Cancer Center Amsterdam for their help in collecting blood and Martijn Bogaarts for technical assistance. This work was financially supported by Marie Curie FP7 ITN NATURIMMUN network.