15353-j-veluchamy

3 HLA independent killing of cervical tumors by UCB-NK cells | 87 t test or a one-way ANOVA with Bonferroni’s multiple comparison test, and a two-way ANOVA with multiple comparisons between column means. Correlation analyses between percentages NK degranulation, cytotoxicity andMFI were performed using Pearson analysis. A P value of < 0.05 was considered statistically significant. Acknowledgements We would like to thank Martijn Bogaarts from the Department of Pathology, VU University Medical Center (Amsterdam, The Netherlands) for technical assistance. We would like to thank all healthy donors who volunteered to give blood for this study. In addition, we would like to thank the Rational Molecular Assessments and Innovative Drugs selection (RAIDs) FP7 Consortium for providing the RAS mutational data on three cell lines included in this study. This work was supported by research grants from the Dutch Cancer Society (KWFVU2013-6015) and the Marie Curie Initial Training Network - The Natural Killer Cell- Based Anti-Cancer Immunotherapies - funded by the European Commission 7th Framework Program (317013).

RkJQdWJsaXNoZXIy MTk4NDMw