15353-j-veluchamy

Chapter 1: General introduction and Scope of this Thesis 7
Chapter 2: Standardized and flexible eight colour flow cytometry panels harmonized between different laboratories to study human NK cell phenotype and function 35
Chapter 3: High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status 73
Chapter 4: Combination of NK cells and cetuximab to enhance anti-tumor responses in RAS mutant metastatic colorectal cancer 95
Chapter 5: In vivo efficacy of umbilical cord blood stem cell-derived NK Cells in the treatment of metastatic colorectal cancer 119
Chapter 6: General discussion and Future Prospects 143
Chapter 7: Summary 163
Nederlandse samenvatting 166
Curriculum vitae 170
List of publications 171
Acknowledgements 173

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