Suzanne de Bruijn

118 Chapter 3.1 32. Salles, F.T., Andrade, L.R., Tanda, S., Grati, M., Plona, K.L., Gagnon, L.H. et al. CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI. Cytoskeleton (Hoboken) 71 , 61-78 (2014). 33. Sakaguchi, H., Tokita, J., Naoz, M., Bowen-Pope, D., Gov, N.S. & Kachar, B. Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport. Cell Motil Cytoskeleton 65 , 528-38 (2008). 34. Pataky, F., Pironkova, R. & Hudspeth, A.J. Radixin is a constituent of stereocilia in hair cells. Proceedings of the National Academy of Sciences 101 , 2601-2606 (2004). 35. Gagnon, L.H., Longo-Guess, C.M., Berryman, M., Shin, J.B., Saylor, K.W., Yu, H. et al. The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. Journal of Neuroscience 26 , 10188-98 (2006). 36. Lalwani, A.K., Goldstein, J.A., Kelley, M.J., Luxford, W., Castelein, C.M. & Mhatre, A.N. Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. American Journal of Human Genetics 67 , 1121-1128 (2000). 37. Gao, K., Tang, W., Li, Y., Zhang, P., Wang, D., Yu, L. et al. Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils. Journal of Cell Science 128 , 992-1000 (2015). 38. Yoon, S., Molloy, M.J., Wu, M.P., Cowan, D.B. & Gussoni, E. C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia. Developmental Biology 301 , 70-81 (2007). 39. Mardakheh, F.K., Self, A. &Marshall, C.J. RHObinding to FAM65A regulates Golgi reorientation during cell migration. Journal of Cell Science 129 , 4466-4479 (2016). 40. Hermjakob, H., Montecchi-Palazzi, L., Lewington, C., Mudali, S., Kerrien, S., Orchard, S. et al. IntAct: an open sourcemolecular interaction database. Nucleic Acids Research 32 , D452-D455 (2004). 41. Cremers, F.P.M., den Dunnen, J.T., Ajmal, M., Hussain, A., Preising, M.N., Daiger, S.P. et al. Comprehensive registration of DNA sequence variants associated with inherited retinal diseases in Leiden Open Variation Databases. Human Mutation 35 , 147-148 (2014). 42. Oonk, A.M.M., Leijendeckers, J.M., Lammers, E.M., Weegerink, N.J.D., Oostrik, J., Beynon, A.J. et al. Progressive hereditary hearing impairment caused by a MYO6 mutation resembles presbyacusis. Hearing Research 299 , 88-98 (2013). 43. Vahava, O., Morell, R., Lynch, E.D., Weiss, S., Kagan, M.E., Ahituv, N. et al. Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans. Science 279 , 1950-1954 (1998). 44. O'Neill, M.E., Marietta, J., Nishimura, D., Wayne, S., Van Camp, G., Van Laer, L. et al. A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6. Human Molecular Genetics 5 , 853-6 (1996). 45. Bayat, A., Saki, N., Nikakhlagh, S., Mirmomeni, G., Raji, H., Soleimani, H. et al. Is COPD associated with alterations in hearing? A systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease 14 , 149-162 (2018).

RkJQdWJsaXNoZXIy ODAyMDc0