Suzanne de Bruijn

137 A RIPOR2 deletion is a frequent cause of adult-onset hearing loss 0.00 0.05 0.10 0.15 0.20 Age (y) Fraction of cases >5-10 >10-15 >15-20 >20-25 >25-30 >30-35 >35-40 >40-45 >45-50 >55-60 >60-65 >65-70 >70 N=50 >50-55 Figure S4. Reported age of onset of hearing loss of subjects with the RIPOR2 c.1696_1707del variant. Distribution of the reported ages of onset of RIPOR2 -associated hearing loss per 5 years for 52 subjects who reported a specific age of onset. y, years.