Suzanne de Bruijn

265 Exploring the missing heritability in subjects with hearing loss and EVA Table S2. Details of applied next generation sequencing methods Case Sequencing method Platform % Reads coverage ≥ 20x Mean coverage (x reads) SLC002 WGS BGISeq500 88.14 36 SLC003 MIPS NextSeq500 94.78 920 SLC012 WGS BGISeq500 88.45 37 SLC013 MIPS NextSeq500 91.78 900 SLC014 MIPS NextSeq500 92.28 815 SLC015 WES Illumina HiSeq2000 96.84 115 SLC017 WES Illumina HiSeq2000 96.70 125 SLC018 WGS BGISeq500 88.77 39 SLC031 MIPS NextSeq500 93.31 517 SLC032 WGS BGISeq500 89.62 43 SLC036 WGS BGISeq500 89.21 41 SLC039 MIPS NextSeq500 93.33 676 WGS BGISeq500 89.21 41 SLC040 WES Illumina HiSeq4000 93.50 136 SLC043 WES Illumina HiSeq2000 94.85 111 SLC045 MIPS NextSeq500 92.28 590 WGS BGISeq500 83.83 30 SLC048 WGS BGISeq500 88.82 38 SLC052 WES Illumina HiSeq2000 93.77 103 SLC056 MIPS NextSeq500 95.21 901 SLC069 WES Illumina HiSeq2000 96.62 130 SLC070 WES Illumina HiSeq4000 97.18 118 SLC071 WES Illumina HiSeq4000 97.33 121 SLC073 MIPS NextSeq500 94.99 880 SLC078 MIPS NextSeq500 95.63 1017 SLC079 WES Illumina HiSeq4000 97.17 101 LRS Sequel II PacBio NA 12 SLC080 WES Illumina HiSeq4000 97.40 115 WGS BGISeq500 85.27 30 SLC084 WES Illumina HiSeq4000 98.01 123 SLC085 WGS BGISeq500 80.33 30 SLC086 WES Illumina HiSeq4000 97.34 123 WES, whole exome sequencing; WGS, short-read whole genome sequencing; MIPS, molecular inversion probe sequencing; LRS, long-read whole genome sequencing; NA, not applicable.