Suzanne de Bruijn

277 Exploring the missing heritability in subjects with hearing loss and EVA Figure S4. Pure tone audiometry of affected individuals. Air, and if available, bone conduction thresholds of all subjects are depicted, except for subjects of the M2 reference cohort. The p95 values are matched to the individuals' sex and age at the most recent audiometry, according to the ISO 7029:2017 standard. The age range for which the ISO 7029:2017 can be applied is 18 to 70 years. Black arrows: threshold could not be measured. The CEVA haplotype was detected in 8 individuals, in an additional 2 individuals (SLC040 and SLC071, indicated with *), a smaller haplotype was found, termed V1-CEVA. y, age in years; R, right; L, left; B, bone conduction; dB HL, decibel hearing level; kHz, kiloHertz.