Maayke Hunfeld

139 Cause of death Supplemental table 2. W/D-Neuro: characteristics of patients with decision WLST (n=42) Nr. Sex (M/F) Time decision WLST a Pre-arrest PCPC Neurological exam b Sedative infusions c Targeted Tempe- rature d EEG e CT brain MRI brain Ultrasound brain DecisionWLST based on f 1 M 0 Mild disability No reactive pupils; No CR; No OCR; Triggering ventilation present; Best Motor score M1 Fentanyl, Propofol - - Hydro-cephalus with diffuse swelling and brain herniation - - Neurologic exam + imaging+ metastatic brain tumor + re arrest 2 M 0 Normal No reactive pupils; No CR; No OCR; Unknown triggering ventilation; Best Motor score M1 Propofol, Sufentanil 33°C - No ischemia; No edema - - Neurologic exam + circulatory failure 3 F 0 Normal Reactive pupils; No CR; OCR ND; No triggering ventilation; Best Motor score M1 No - - Diffuse swelling and brain herniation Diffuse ischemia cortex, BG - Neurologic exam + imaging + severe damage craniocervical junction 4 F 0 Normal No reactive pupils; CR ND; OCR ND; triggering ventilation ND; Best Motor score M1 Midazolam, Rocuronium, Ketamine - - Diffuse swelling and brain herniation - - Neurologic exam + imaging + traumatic decapitation of the cervical spine with major dislocation of the dense 5 F 0 Normal No reactive pupils; No CR; No OCR; No triggering ventilation; Best Motor score M1 Fentanyl, Propofol 37°C - No ischemia; No edema - - Neurologic exam + immeasurably high intracranial pressure 6 M 0 Normal No reactive pupils; No CR; No OCR; No triggering ventilation; Best Motor score M1 Propofol 34°C - No ischemia; No edema - - Neurologic exam + fulminant meningitis 7 F 0 Normal No reactive pupils; NoCR; No OCR; triggering ventilationND; BestMotor scoreM1 No 33°C - Diffuse swelling - - Neurologic exam + imaging 8 F 0 Normal No reactive pupils; NoCR; No OCR; No triggering ventilation; BestMotor scoreM1 Fentanyl 33°C - - - - Neurologic exam + circulatory failure + poor ECMO output 9 F 0 Normal No reactive pupils; NoCR; No OCR; triggering ventilationND; BestMotor scoreM1 Midazolam 34°C - Diffuse swelling and brain herniation - - Neurologic exam + imaging 10 M 0 Normal No reactive pupils; No CR; No OCR; No triggering ventilation; Best Motor score M1 No 34°C Low voltage Diffuse swelling - - Neurologic exam + EEG + imaging 4