Maayke Hunfeld

14 Chapter 1 Manglick et al. had a follow-up interval up to 5 years after event, but they included only children post-drowning who were neurologically intact at hospital discharge (44). Actual research question: What is the long-term longitudinal (with repeated measures) physical and neuropsychological outcome of pediatric OHCA survivors? Author Journal Year N Age at arrest (range) Inclusion criteria Follow-up interval Outcome Suominen Resuscitation (45) 2014 20 Median 2.4 years (IQR 1.8-5.5 years) near-drowning with cardiac arrest Cross- sectional, median 8 years after arrest Full scale IQ 40% below 80 Slomine Pediatrics (42) 2015 < 6 years n=42 ≥ 6 years n=18 0-17.9 years OHCA Unresponsive and mechanical ventilation after ROC 1 year < 6 years: Mullen scale: -Early learning composite 82% below 85 -Visual reception 70% below 85 -Fine motor 71% below 85 -Receptive language 71% below 85 -Expressive language 79% below 85 ≥ 6 years: Full-scale IQ 38% below 85 All ages: VABS II: Worse all domains compared with baseline, 49% ≥ 70 Van Zellem Intensive Care Medicine (5) 2016 47 0-16.1 years IHCA/OHCA Cross- sectional, median 5.6 years after arrest Full scale-IQ, VIQ, PIQ lower than norm data Worse scores on long- term visual memory Better scores on long-term verbal memory