Maayke Hunfeld

153 MRI and prognosis With MRI 1 n=40 No MRI 1 n=59 p value 2 Age months 57 (9-172) 32 (11-103) 0.207 Gender male 27 (68 ) 38 (64) 0.831 Year OHCA 2015 (2012-2017) 2014 (2013-2016) 0.960 Bystander CPR 35 (88 ) 40 (68) 0.032 * Initial rhythm shockable Missing, n 13 (39 ) 7 7 (16) 15 0.034 * Duration CPR (min) Missing, n 16 (7-25) 12 15 (3-46) 29 0.294 First lactate (mmol/L) Missing, n 9.7 (4.6-16) 0 13.1 (6.4-17) 10 0.118 First pH Missing, n 7.0 (6.8-7.2) 1 7.0 (6.8-7.2) 10 0.993 Etiology arrest Cardiac Respiratory Other 13 (33) 16 (40) 11 (27) 18 (30) 23 (40) 18 (30) 0.812 Survival to hospital discharge 27 (68) 22 (37) 0.004 * PCPC discharge survivors 2 (1-3) 2 (1-2) 0.050 Timing WLST (days) 4 (4-7) 0 (0-1) 0.002 * Brain death 4 (31) 13 (35) >0.999 WLST-neuro 9 (69) 22 (60) 0.742 Re-arrest or WLST cardio/resp 0 (0) 2 (5) >0.999 Table 1. Basic characteristics of children with and without brain MRI post-OHCA 1 Data are presented as n (%) or median (IQR: 25 th -75 th percentile) 2 Mann-Whitney U for continuous and fisher exact for categorical data *p < 0.05 for differences in basic characteristics for MRI versus non-MRI group CPR=cardiopulmonary resuscitation, PCPC=pediatric cerebral performance category scale, OHCA= out-of-hospital cardiac arrest, SES=socio-economic status, WLST=withdrawal of life sustaining therapies. 5

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