Maayke Hunfeld

183 Shockable rhythm and outcome Overall Favorable outcome Non-favorable outcome (n = 360) (n = 115) (n = 244) n a n a n a p-Value d Missings c First lactate (mmol/L) after ROSC or after hospital arrival b 328 12.7 5.1 - 16.0 105 4.4 2.4 - 7.6 223 15.0 10.7 - 19.0 <0.001 32 9% Post cardiac arrest characteristics Post-ROSC ECMO c 360 12 3% 115 5 4% 245 7 3% 0.534 0 Temperature management c 354 149 42% 115 47 41% 239 102 43% 0.819 6 2% Re-arrest c 360 13 4% 115 6 5% 245 7 3% 0.364 0 Outcome Sustained ROSC c 360 258 72% 115 115 100% 245 143 58% <0.001 0 - Before arrival to hospital 204 57% 108 94% 96 39% <0.001 - After arrival to hospital 54 15% 7 6% 47 19% 0.001 Withdrawal of life sustaining therapies c 354 76 21% 115 0 0% 241 76 32% NA 4 1% Survival to hospital discharge c 360 142 39% 115 115 100% 245 27 11% <0.001 0 Deceased after discharge c 360 7 2% 115 0 0% 245 7 3% NA 0 Follow-up Follow-up (months) b 141 25.2 5.1 - 49.6 115 26.3 1.6 - 49.5 19 14.2 9.1 - 67.9 0.779 Age at follow-up (years) b 141 6.6 3.4 - 13.4 115 8.1 3.5 - 14.7 19 5.3 3.0 - 12.1 0.300 Table 1. Patient and cardiac arrest characteristics by primary outcome measure: survival with favorable neurological outcome. AED = Automatic external defibrillator, BLS = Basic life support, EMS = Emergency medical support, CPR = Cardiopulmonary resuscitation, ECMO = Extracorporeal cardiopulmonary support, ECPR = Extracorporeal cardiopulmonary resuscitation, VF = Ventricular fibrillation, ICP = Intracranial, NA = Not applicable pressure, PEA = Pulseless electric activity, ROSC = Return of spontaneous circulation. a Number of subjects in whom the variable was obtained. b Median (interquartile range). c Number of subjects (%). d p-Value: independent sample t-test for continuous data or Mann–Whitney U test dependent on normality; Fisher’s exact test for dichotomous data. 6

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