Maayke Hunfeld

186 Chapter 6 Survival with post-arrest PCPC 1-2 or ∆ PCPC 0 Survival with post-arrest PCPC 1-3 or ∆ PCPC 0 at the longest follow-up interval f (n = 360) at the longest follow-up interval g (n = 360) Crude Adjusted Crude Adjusted Variable OR [95%CI] p-Value OR [95%CI] p-Value OR [95%CI] p-Value OR [95%CI] p-Value Initial non-shockable rhythm a referent referent referent referent Initial shockable rhythm a 8.4 [4.2 - 16.8] <0.001 8.9 [3.1 - 25.9] <0.001 9.4 [4.7 - 18.9] <0.001 13.7 [4.6 - 40.9] <0.001 Initial unknown rhythm a 29.6 [14.6 - 60.3] <0.001 6.1 [2.2 - 16.5] <0.001 31.5 [15.1 - 65.8] <0.001 5.7 [2.1 - 15.8] 0.001 AED use b 1.1 [0.5 - 2.4] 0.873 0.3 [0.1 - 1.0] 0.049 1.1 [0.5 - 2.4] 0.798 0.2 [0.1 - 0.9] 0.035 Bystander BLS c 4.3 [2.4 - 7.8] <0.001 1.9 [0.8 - 4.3] 0.137 3.6 [2.1 - 6.2] <0.001 1.3 [0.6 - 3.0] 0.492 Year of arrest d 1.1 [1.1 - 1.2] <0.001 1.2 [1.1 - 1.2] <0.001 1.1 [1.0 - 1.1] <0.001 1.2 [1.1 - 1.2] <0.001 Post AED guideline change e 2.5 [1.6 - 4.1] <0.001 2.6 [1.3 - 5.1] 0.007 2.3 [1.5 - 3.7] <0.001 2.1 [1.1 - 4.1] 0.028 Table 3. Univariable and multivariable logistic regression analyses of all children with survival with favorable neurologic outcome as dependent variable. AED = Automatic external defibrillator, BLS = Basic life support, CPR = Cardiopulmonary resuscitation, PCPC = Pediatric Cerebral Performance Category ROSC = Return of spontaneous circulation. a Adjusted for witnessed arrest, bystander CPR, age at arrest, year of event, first lactate, pre-existing conditions related to event and CPR duration. b Adjusted for initial rhythm (shockable/non-shockable/unknown), bystander CPR, age at arrest, year of event, first lactate, socio-economic status and CPR duration. c Adjusted for initial rhythm (shockable/non-shockable/unknown), year of event, first lactate, socio-economic status and CPR duration. d Adjusted for initial rhythm (shockable/non-shockable/unknown). e Adjusted for initial rhythm (shockable/non-shockable/unknown), bystander CPR, age at arrest, socio-economic status and CPR duration. f Favorable neurologic survival defined as a post-arrest PCPC of 1-2 or a ∆ PCPC of 0. g Favorable neurologic survival defined as a post-arrest PCPC of 1-3 or a ∆ PCPC of 0.