Maayke Hunfeld

213 Neuropsychological outcome Correlation PCPC and intellectual functioning No correlations were found between PCPC scores and total, verbal, or performance IQ scores on both moments: at 3-6 months, r ranged from -0.10 to 0.08; at 24 months, r ranged from -0.15 to -0.05, data not shown. Discussion To our knowledge, this is the first prospective, longitudinal study on neuropsychological outcomes in paediatric OHCA survivors over a 24 months period. Among survivors, 3-6 and 24 months post-OHCA respectively 74% and 73% had good outcome expressed in PCPC, defined as score 1-2. Only a minority had motor deficits on neurological exam. The majority of school-aged children (81%) went back to school without change in school level after 24 months. Worse scores were found on sustained attention and processing speed compared with norm data at both time-points. Additionally, at 24 months, worse scores were also found on intellectual functioning, selective attention, and cognitive flexibility compared with norm data. In children who underwent neuropsychological testing at both time points no significant changes in neuropsychological outcomes were found over time. Intelligence scores of OHCA children did not correlate with their PCPC scores. Functional outcomes The finding that only a minority (around 15%) of our survivors showed motor deficits at neurological exam 3-6 and 24 months post-OHCA seems in contrast with the findings of the THAPCA trial that reported neurological impairments in 55% of children 1 year post-arrest (28). However, in the THAPCA trial these impairments were not only based on motor function but also on language production and comprehension, cognition and behaviour, making comparison with only motor deficits in our cohort difficult. In our cohort, PCPC scores at hospital discharge (73% 1-2) were in line with those reported by previous research (1, 6, 12) . Silverstein et al. showed that PCPC scores of paediatric OHCA survivors at hospital discharge significantly correlated with PCPC at 3 and 12 months (29) . Our findings at 3-6 and 24 months suggest the same since the percentage of patients with good outcome at discharge remained unchanged over time. 7