Maayke Hunfeld

221 Neuropsychological outcome Supplementary file 2. Overview neuropsychological measures Measurements Test Age (yrs.) Test mean, standard deviation (SD) Notes Intellectual functioning Bayley Scales of Infant Development (BSID-2 or Bayley-3) 0-2.5 Mean 100, SD 15 [1] Intelligence or developmental quotient standard scores. Higher scores represent better functioning. Due to the small sample size, the outcomes of the different tests are grouped: Total IQ score is based on BSID- cognitive score, WPPSI-III TIQ, WISC-III TIQ, or WAIS- IV TIQ. The Verbal IQ score is based on: WPPSI-III VIQ, WISC-III VIQ, WAIS-IV VC-index. The performance IQ score is based on: WPPSI-III PIQ, WISC-III PIQ, WAIS-IV PO-index Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III) 2.6-6 Mean 100, SD 15 [2] Wechsler Intelligence Scale for Children (WISC-III) 7-15 Mean 100, SD 15 [3] Wechsler Adult Intelligence Scale (WAIS-IV) 16-18 Mean 100, SD 15 [4] Selective attention Stroop Color Word Test (Stroop) ≥ 11 Mean 50 SD10 [5] T-score; Higher scores represent better functioning Sustained attention Bourdon Vos cancellation test ≥ 6 Mean 0, SD1[6] Z-score compared with age appropriate scores; Higher scores represent better functioning Processing speed Age-appropriate versions of the Wechsler Scales (WPPSI-III, WISC- III, WAIS-IV) ≥ 4 Mean 100, SD 15 [2-4] Standard norm score: Higher scores represent better functioning Visual-Motor Integration Beery Developmental Test of Visual Motor Integration (Beery-VMI) ≥ 2 Mean 100, SD 15 [7] Standard norm score: Higher scores represent better functioning Verbal memory: delayed recall Rey auditory verbal learning test (Rey-AVLT) ≥ 6 Mean 0, SD1[8, 9] Z-score compared with age appropriate scores: Higher scores represent better functioning Visual memory: recognition Rey-Osterrieth Complex Figure test (Rey CFT) ≥ 6 Mean 50, SD 10 [10] T-score: Higher scores represent better functioning Executive functions: flexibility Trail Making Test part B (TMT-B) ≥ 8 Mean 0, SD1[11] Z-score compared with age appropriate scores: Higher scores represent better functioning Parent-reported executive function questionnaire Behaviour Rating Inventory of Executive Function questionnaires (BRIEF-P and BRIEF) ≥ 2 Mean 50, SD 10 [12] T-score; A higher score means worse functioning (more reported problems) 7

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