Maayke Hunfeld

53 Review neuromonitoring EEG classification EEG timing Results Mortality (%) Limitations EBM Grade -Normal -Slow-disorganized -Discontinuous-BS -Attenuated-flat cEEG onset: within 1 day of ROSC for > 24 hrs -Worse background EEG and absence of reactivity early after CPR associated with mortality and poor neurologic outcome (P<0.001) -Each incrementally worse background score led to an odds of death of 3.63 (95% CI 2.18-6.0, p<0.001) and an odds of unfavourable NO of 4.38 (95% CI 2.51- 7.17, p = 0.001) -IHCA vs OHCA: no difference in seizures or survival to discharge. IHCA more likely to have a slow and disorganized background category and favourable neurological outcome 42% -Retrospective -Non-blinded physicians -PCPC by chart review -EEG report review instead of EEG tracings -Some children with initial flat or BS EEG had a good outcome. -Only short and crude outcome 2B 0=Normal 1=Slow organized 2=slow, disorganized, 3=discontinuous 4=BS 5=Suppression Onset cEEG: mean 18hrs post ROSC (good outcome) , 10 hrs (poor outcome) post ROSC for > 24 hrs post ROSC -EEG score 0 or 1, normal voltage, reactivity and variability within 12 hrs post ROSC with CA < 20 minutes significantly associated with good outcome (P<0.05) -EEG score 4 or 5 within 12 hrs post ROSC associated with poor outcome (P?) -Association between poor outcome and moderate seizure burden and status epilepticus (not sign, P=0.17) Unspecified -Retrospective -Non-blinded -Short and crude outcome -18-21% of children with normal EEG poor outcome -Duration of EEG monitoring epochs varied 2B 2