Maayke Hunfeld

58 Chapter 2 5. MRI BRAIN Source/ Year Inclusion period Study type Number of centers N Age group Hypo- thermia TimingMRI MRI sequences Outcome score Follow up interval Dubowitz 1998 (31) 1991-1997 Retro- spective 1 N=22 Mean 3.5 yrs (6mo-11yrs) no -MRI performed mean 2.2 days (1-6) post ROSC N=17 second MRI mean 2.9 days (2-5) N=6 third MRI mean 8.90 days MRI (4-16) -Axial spin-echo, T1, repetition time/echo, Gradient echo and T2. MR spectroscopy CPC (1-2 = good outcome) Timing not specified Fink 2013 (32) 2002-2008 Retro- spective 1 N=28 Median 1.9 yrs (IQR 0.4-13) 68 % (Depended on PICU physician -MRI performed median 6 days (IQR 4-11) post ROSC -T1, T2 and DWI/ ADC GOS (4-5 = good outcome) Hospital discharge