Joris van Dongen

159 The power of fat and ASCs for scar treatment: a review Follow up Results Complications Pain evaluation using a VAS (mean follow-up of 13 months). Decrease of pain in treated group compared to untreated group.** No complications reported Pain evaluation using VAS and NPSI scores (pre-operative, 1 week, 4 weeks and 24 weeks postoperative). Decrease of VAS and VSS scores after 1, 4 and 24 weeks compared to preoperative scores.** No other comparisons between postoperative measurements performed. No effect in 2 cases. No complications reported Pain and skin quality of the scar was evaluated using the POSAS questionnaire (without control group). Scar hardness was measured using the durometer (with control group). Both after 3 months. All POSAS scores (patient and observer scores) decreased significantly except for itching. Scars hardness decreased postoperative compared to preoperative in the treated group.* No significant decrease of scar hardness No complications mentioned Evaluation of spontaneous pain using a VAS (preoperative and 1 year postoperative). Amean decrease of pain of 3.1 in the treated group and 0.9 in the control group. More decrease of pain in the treated group compared to the control group.** No complications reported Functional results were evaluated using the LENT-SOMA scoring system, 3 months after the last treatment. Aesthetic results were evaluated using a 5-grade scale. Scores for pain, telangiectasia, breast edema, atrophy and fibrosis decreased in the intervention group after 3 months.** No significant difference for above mentioned scores compared to the control group after 3 months. Aesthetic outcome improved in the intervention group compared to the control group.* No significant complications reported LENT-SOMA grading scale scores evaluation (mean follow-up of 30 months). Reduction of LENT-SOMA grading scale scores.** Improvement observed in all patients, except 1 case. No complications reported Perineal pain evaluation using a MGPQ, a PPI and VAS. The SSSRS was used to evaluate the sexual satisfaction of the patients. (preoperative, 1, 3 and 6 months). Reduction of pain after 1, 3 and 6 months in all pain questionnaires.* Improvement in sexual satisfaction after 1, 3 and 6 months.* No comparison performed between postoperative time points. No major complications reported Mastectomy Radiotherapy, PMPS = Post-Mastectomy Pain Syndrome, VAS = Visual Analogue Scale, NPSI = Neuropathic Pain Symptom Inventory, MGPQ = McGill Pain Questionnaire, PPI = Present Pain Intensity index, SSSRS = Sabbatsberg Sexual Self-Rating Scale * Significant difference (p<0.05) ** Significant difference (p<0.001)

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