Joris van Dongen

205 PRP enriched facial lipofilling significant smaller (harvester: 2.4mm x 22cm, injector: 0.9mm x 5cm). The upper legs served as donor site in all patients. Location and applied lipofilling volume is presented in Figure 3. All procedures have been performed by the same surgeon (HPS), who at that time had already experience with more then 2000 lipofilling procedures. A detailed, step-by-step description of the lipofilling procedure is available online as video supplement 5 . Figure 3. Lipofilling locations and applied volume. Both superficial and deep lipofilling was performed on both sides of the face. In total 18cc per side, 36cc in total. Within the PRP group, 3cc of PRP was added into the lipofilling planes. Legend: Deep: Temporal projection (red), Nasojugal groove (green), Central midface (yellow), Nasolabial-fold (blue), Marionette line, Pre-jowling area and chin (pink). Superficial: Temporal and central midface area (white), Lower midface-cheek area (black), White rolls (cyan). Skin measurements Local skin quality was measured with the Multi Probe Adapter system (C&K Colone Germany) containing the Cutometer MPA580 (elasticity) probe. The cutometer is a valid method in objectifying elasticity of the skin 12-16 . Measurements were done on fixed locations for every patient (Fig. 2) at every follow-up moment. Before each measurement, the probes were calibrated and tested for correct function. Also local temperature and humidity were logged. True skin elasticity was defined by the