Joris van Dongen

231 tSVF enriched facial lipofilling with PRP FACE-Q The following FACE-Q were examined at the predetermined time-points except for 3 months postoperative: satisfaction with facial appearance overall, satisfaction with facial skin, appraisal of lines overall, appraisal of crow’s feet lines, age appraisal with the use of visual analogue scale (VAS), aging appearance appraisal, psychological wellbeing, social function and satisfaction with outcome. Recovery of early symptoms and recovery early life impact were only examined one week postoperative. All questionnaires were validated and translated to Dutch using a linguistic validation. Raw FACE-Q scores were converted to RASCH scores according to the protocol of the FACE-Q editorial board. 26 VAS scores of age appraisal were not converted to RASH scores. FACE-Q scores of 155 Caucasian Dutch women between 18 and 80 years old who have never received any aesthetic facial procedure where asked to complete the baseline FACE-Q modules and served as control. Statistical Analysis Statistical analysis was performed under supervision of an independent statistician (KMV) that received blinded data from the first author (JAD) and the randomization from the senior author (HPS). All analysis was done with the use of SPSS 20 (IBM, Chicago, IL, USA). Prism 6 was used to design the graphs (GraphPad software, La Jolla, CA, USA). Visual inspection revealed normally distributed data for the cutometer and VISIA analysis, thus a paired samples t -test and regular t- test were used to analyze the outcomes of the cutometer and VISIA analysis. AWilcoxon Signed Ranks test and Mann-Whitney test were used for the FACE-Q data.A two-sided p<0.05was considered statistically significant. RESULTS Demographics and platelet counts A total of twenty-eight subjects were enrolled in this study with twenty-five subjects completed the entire study (tSVF = 14, control = 11). Only twenty-eight of the calculated sixty-four subjects were included because the required pace of inclusion was not met endanger completion of the study. Four subjects failed to complete each follow-up moment of the study; one subject underwent a facial aesthetic procedure after six months of follow-up, two subjects did not show-up for the last follow-up moment and one subject missed only the six months follow-up moment due to personal circumstances. Fourteen subjects were included in both study arms (Table 2). Mean age