Joris van Dongen

239 tSVF enriched facial lipofilling with PRP Figure 8. Changes in FACE-Q regarding satisfaction with facial appearance overall are presented between both the experimental and control group for all timepoints. * A higher satisfaction with facial appearance overall was shown in the control group as compared to the experimental group twelve months postoperative (p<0.05). tSVF = tissue stromal vascular fraction. DISCUSSION The addition of tSVF to autologous facial lipofilling with PRP did not show benefits for skinqualityforaesthetic reasons, recoveryorsubject satisfaction in this study.Lipofilling with PRP alone did not improve skin quality compared to preoperative values, while patient satisfaction for overall facial appearance was improved. In literature, clinical reports studying autologous lipofilling or any component of adipose tissue e.g. cSVF or tSVF as a treatment of facial skin quality show different results compared to this prospective randomized controlled trial. 27-31 Those reports mentioned improvement in skin quality e.g. skin texture, wrinkles and pores size. However, the level of evidence in those clinical studies does not allow to draw strong conclusions. 1 Thus, those results should be interpretedwith caution. To date, only onewell-designed prospective double- blinded randomized controlled trial showed no increase of facial skin elasticity after treatment with autologous lipofilling with or without PRP. 12 However, a regression