Birgitta Versluijs

69 HRCT after hematopoietic cell transplantation Results Patients During the study period, 124 chest HRCT examinations were performed in 72 child- ren after hematopoietic cell transplantation. The mean interval between hematopoietic cell transplantation and chest HRCT was 84 days. For our study, we only used the first HRCT study because disease episodes may be interrelated. In 52 children, HRCT was performed because of early respiratory symptoms within 100 days after hematopoietic cell transplantation: 18 children had allo-LS and 34 had nonallo-LS. The 18 patients with allo-LS all had symptoms during recovery of immunity, none had significant signs of infection (fever or raised C-reactive protein [CRP]), and all had initial improvement on immunosuppressive therapy. Most nonallo-LS patients had an infection, suggested by fever, raised CRP, or positive microbial tests. TABLE 2. Chest high-resolution CT scoring system for pulmonary complications in hematopoietic cell transplant patients. Per lobe Score 0 Score 1 Score 2 Score 3 Bronchiectasis Absent <33 33-67 >67 Airway wall thickening Absent <33 33-67 >67 Tree-in-bud pattern Absent Limited Marked Extensive Nodules Absent Limited Marked Extensive Consolidation Absent <33 33-67 >67 Ground-glass pattern Absent <33 33-67 >67 Septa thickening Absent Mild Moderate Severe Airtrapping Absent <33 33-67 >67 Note—Numeric data are percentages of lobar volume involved. The score was applied to each lobe, including the lingula, leading to a range of 0–18. The composite score is the sum of the eight item scores, ranging from 0 to 144. Scores were then expressed on a 0–100 scale as percentage of maximum score to make interpretation easier. 4