Birgitta Versluijs

70 Results Interobserverd agreement for high-resolution CT scoring The between-observer agreement was moderate to good for all items except septa thick- ening and airway wall thickening. The within-observer agreement was moderate to good for all items. The composite score had good agreement both between and within obser- vers. Further details are presented in Table 3. TABLE 3. Within-observer and between-observer agreement of HRCT score. Finding Within-observer agreement Between-observer agreement Bronchiectasis 0.81 0.70 Airway wall thickening 0.78 0.59 Tree-in-bud pattern 0.78 0.66 Nodules 0.78 0.71 Consolidation 0.79 0.86 Ground-glass pattern 0.90 0.71 Septa thickening 0.80 0.53 Airtrapping 0.77 0.75 Composite score 0.92 0.80 Note—Data are intraclass correlation coefficients: < 0.6, no agreement; 0.6–0.8, moderate agreement; > 0.8, good agreement. Prevalence of high-resolution CT abnormalities for the various pulmonary complications early after hematopoietic cell transplantation The prevalence of individual HRCT abnormalities overlapped substantially between allo- LS and nonallo-LS groups (Table 4). Consolidations and ground-glass pattern were seen in more than half of the patients; tree-in-bud pattern was relatively rare. Only for ground- glass pattern, there was a significantly higher prevalence in the allo-LS group compared with the nonallo-LS group. Severity score of high-resolution CT abnormalities for pulmonary complications early after hematopoietic cell transplantation In allo-LS, the HRCT scores for ground-glass pattern and airtrapping were significantly higher than in nonallo-LS (Table 5). This was also true for the total of all abnormali- ties (composite-score). For the early pulmonary complications, we made an allo-score by combining the two individual parameters that had shown to be significantly different in 4

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