Birgitta Versluijs

74 Discussion Discussion In this study, we describe the development of an HRCT score for patients with respira- tory complications after hematopoietic cell transplantation. There is a large overlap in the presence of individual HRCT abnormalities in allo-LS and nonallo-LS, such as in- fection or toxicity. The HRCT severity score can differentiate between these two groups of diseases, especially in the early phase after transplantation. FIGURE 2. Examples of chest high-resolution CT (HRCT). A and B, Chest HRCT images in 7-year-old girl early after hematopoietic cell transplantation with respiratory symptoms. Com- posite HRCT score was 10 and “allo-score” (ground-glass pattern + airtrapping) was 0. Final diagnosis was toxicity. C and D, Chest HRCT images in 2-year-old boy early after hemato- poietic cell transplantation with respiratory symptoms. Composite HRCT score was 10 and allo-score was 31. Final diagnosis was idiopathic pneumonia syndrome. 4