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Chapter 7 182 0 2 4 6 8 0 2 3 4 5 6 Weeks Belching (11-point NRS) Placebo Small-intestinal release peppermint oil Ileocolonic release peppermint oil * * Figure S7.6 Belching scores in the ITT-population ( N =189). Values are adjusted estimated marginal means derived from the linear mixed model, bars represent standard errors. The small- intestinal peppermint oil group had significantly more increase in belching at the week 1 and 2, * P =0.0003, and * P =0.023, respectively. The Ileocolonic release peppermint oil group did not differ significantly in belching compared with placebo. Assessed weekly on an 11-point NRS in the digital symptom diary.