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Chapter 7 186 analysis showed that baseline mean worst abdominal pain was not a significant effect modifier of treatment group and the primary abdominal pain response outcome (LR test P =0.322). Similarly, when dividing patients into two groups based on baseline mean worst abdominal pain, i.e. a group with the lowest 2/3 of baseline abdominal pain and a group with the highest 1/3 of baseline abdominal pain, the proportion of abdominal pain responders did not differ significantly between groups ( P =0.086).

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