Dorien Bangma

84 | CHAPTER 4 Study Country Design Sample characteristics FDM task (scale) Main outcome Conclusion Marson et al. (2009) + USA CS AD (n=31) / Stage: moderate SCIFC (scores on domains 1-8, total score based on domains 1-7) - People living with moderate AD were more often marginally capable or incapable regarding FDM than HC on the SCIFC total score and on all domains separately. - People living with mild AD were more often marginally capable or incapable regarding FDM than HC on the SCIFC total score and on all domains separately, with the exception of ‘basic monetary skills’. - People living with moderate AD were more often marginally capable or incapable regarding FDM than people living with mild AD on the SCIFC total score and on all domains separately, with the exception of ‘checkbook management’ and ‘bill payment’. AD (moderate) ≤ AD (mild) ≤ HC - age (y) 75.3±8.4 * - education (y) 11.1±3.7 * § - 32.3% male *§ - MMSE 16.4±4.2 * § - DRS 90.7±19.6 * § - CDR 1.0 to 3.0 ? AD (n=97) / Stage: mild - age (y) 72.4±8.4 * - education (y) 13.4±2.1 * - 53.6% male - MMSE 24.0±3.1 * - DRS 114.0±12.1 * - CDR 0.5 to 1.0 ? HC (n=75) - age (y) 66.1±7.7 - education (y) 14.3±1.6 - 32.0% male - MMSE 29.3±1.0 - DRS 138.7±3.8 - CDR 0.0 or 0.5 Martin, Griffith et al. (2008) USA LS AD (n=55) / Stage: mild FCI (scores on domains 1-9, total score based on domains 1-7, total score based on domains 1-8) - People living with mild AD showed a significant deterioration after 1 year on the FCI total scores and on all domains separately. No significant deterioration was observed in HC. N/A - age (y) 70.6±8.4 * - education (y) 13.1±2.3 * - 56.4% male * - MMSE 24.5±3.1 * - DRS 116.2±10.5 * - CDR 0.5 or 1.0 * HC (n=63) - age (y) 66.3±7.6 - education (y) 14.4±1.7 - 31.7% male - MMSE 29.3±1.0 - DRS 136.7±4.8 - CDR 0 e Martin et al. (2019) + USA CS AD (n=54) / Stage: mild FCI (scores on domains 1-9, total score based on domains 1-7, total score based on domains 1-7, 9) - People living with mild AD showed significantly lower FDM performances than HC on the FCI total scores and on all domains separately. AD (mild) < HC - age (y) 73.3±8.2 * - education (y) 13.7±3.2 * - 53.7% male - MMSE 24.5±3.2 * - DRS 118.4±12.0 * - CDR 0.5 to 1.0 HC (n=82) - age (y) 66.3±8.5 - education (y) 15.2±2.5 - 36.6% male - MMSE 29.5±0.9 - DRS 138.9±3.7 - CDR 0.0 or 0.5 Pereira, Yassuda et al. (2010) + Brazil CS AD (n=26) / Stage: n.r. Subscale ‘financial skills’ of DAFS – Brazilian version (total score) - People living with AD showed a significantly lower FDM performance than HC on the total score of the ‘financial skills’ subscale. AD < HC - age (y) 77.9±6.0 * - education (y) 8.8±5.5 * - 42.0% male ? - MMSE 19.5±5.5 * HC (n=32) - age (y) 71.6±5.6 - education (y) 13.3±6.0 - 25.0% male - MMSE 28.8±1.5 Sherod et al. (2009) + USA CS AD (n=43) / Stage: mild FCI (total score based on domains 1- 7) - People living with mild AD showed a significantly lower FDM performance than HC on the FCI total score. AD (mild) < HC - age (y) 73.8±8.5 * - education (y) 13.6±2.9 * - 55.8% male - MMSE 24.6±2.9 * - DRS 118.7±10.2 * - CDR 0.5 to 2.0 * HC (n=85) - age (y) 67.2±8.2 - education (y) 15.0±2.4 - 35.3% male - MMSE 29.4±0.9 - DRS 138.8±3.3 - CDR 0 or 0.5 Table continues on the next page